Rogue · Assassination · PvE · level 50 of 60

Assassination Rogue endgame PvE build at level 50

Mutilate, Seal Fate, Venom, Vile Poisons, Improved Poisons and Relentless Strikes with Precision, Puncturing Wounds, Dual Wield Specialization and Efficient Strikes.

Talents at level 50

TalentTreeRankTaken at
MaliceAssassination5/510, 11, 12, 13, 14
RuthlessnessAssassination3/315, 16, 17
Improved Slice and DiceAssassination2/318, 19
VigorAssassination2/220, 21
Blood SplatterAssassination1/122
LethalityAssassination2/223, 24
Coup de GraceCombat3/325, 27, 29
Vile PoisonsAssassination5/526, 28, 30, 32, 34
Efficient StrikesCombat2/231, 33
Puncturing WoundsCombat3/335, 37, 39
Cold BloodAssassination1/136
Improved PoisonsAssassination5/538, 40, 42, 44, 46
DeflectionCombat2/341, 43
PrecisionCombat3/345, 47, 49
Relentless StrikesAssassination2/548, 50

Next five points (51–55)

  1. Level 51: Endurance (Combat)
  2. Level 52: Venom (Assassination)
  3. Level 53: Endurance (Combat)
  4. Level 54: Seal Fate (Assassination)
  5. Level 55: Aggression (Combat)

Notes that apply by 50

  • Daggers: Mutilate with Puncturing Wounds crit, Seal Fate for double combo points, Shank then Venom for 30% poison damage. Deadly Poison main hand, Instant Poison off hand.
  • Rupture with Blood Splatter lasts 6 seconds longer; Cold Blood into Eviscerate for burst.

Questions players ask

What should a level 50 Assassination Rogue have in its talent trees?
Malice 5/5, Ruthlessness 3/3, Improved Slice and Dice 2/3, Vigor 2/2, Blood Splatter 1/1, Lethality 2/2, Coup de Grace 3/3, Vile Poisons 5/5, Efficient Strikes 2/2, Puncturing Wounds 3/3, Cold Blood 1/1, Improved Poisons 5/5, Deflection 2/3, Precision 3/3, Relentless Strikes 2/5: 28/13/0 across Assassination/Combat/Subtlety. That is every point from 10 to 50 in the order this build replays.
What comes next after level 50?
Endurance at 51, Venom at 52, Endurance at 53, Seal Fate at 54, Aggression at 55. The full order to 60 is on the build page.
Can I open the calculator at this level?
Yes. The link below opens the Rogue talent calculator with the level set to 50, so only the first 41 points of the order are shown and you can continue from there.